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. 2014 Aug 12;53(34):5485–5495. doi: 10.1021/bi5006249

Figure 1.

Figure 1

TRF-mediated telomeric D-loop formation. (A) Diagram of the D-loop assay. (B) TRF2 and TRF2ΔB promote telomeric D-loop formation with an activity peak when included at a final protein concentration between 100 nM (lane 3) and 150 nM (lane 4). (C) TRF2ΔM and TRF1 promote telomeric D-loop formation only at higher concentrations.