Fig. 5.
KJ-Pyr-9 interferes with the growth of a xenograft of MDA-MB-231 cells. Mice were injected with 5 × 106 MDA-MB-231 cells s.c. into the left and right flanks. When tumors reached a volume of 100 mm3, half of the mice were given daily i.p. injections of 10 mg/kg KJ-Pyr-9 and the other half received vehicle only. Tumor growth was followed for 31 d. (A) Tumor volumes of treated and untreated animals. (B) Tumor weights of treated and untreated animals. (C) Time course of tumor volumes. Error bars indicate 95% confidence intervals.