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. 2014 Jul 29;45(4):1372–1380. doi: 10.3892/ijo.2014.2569

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Copyright © 2014, Spandidos Publications

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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Hospicells protect HL60 cells against daunorubicin effect in the presence of IGF-I. HL60 was co-cultivated with Hospicells in the presence of IGF-I alone or with PPP. The chemotherapy agent, daunorubicin was added to the culture medium for 24 h (A). HL60/Dnr cells co-cultivated with Hospicells from AML N3 in the presence of IGF-I or PPP during 24 h and were incubated thereafter with daunorubicin (B). Average ± SE, (n=3), the difference in expression is significant (^*P<0.05, ^***P<0.0005).

Hospicells protect HL60 cells against daunorubicin effect in the presence of IGF-I. HL60 was co-cultivated with Hospicells in the presence of IGF-I alone or with PPP. The chemotherapy agent, daunorubicin was added to the culture medium for 24 h (A). HL60/Dnr cells co-cultivated with Hospicells from AML N3 in the presence of IGF-I or PPP during 24 h and were incubated thereafter with daunorubicin (B). Average ± SE, (n=3), the difference in expression is significant (^*P<0.05, ^***P<0.0005).