Table 1.
WWOX Mutations in Cancer
| Case ID | Cancer Study | AA Change | Type | Mutation Assessor | |
|---|---|---|---|---|---|
| TCGA-AX-A05Z | Uterine (TCGA ) (36) | D267Y | Missense | Low | |
| TCGA-AX-A2H5 | Uterine (TCGA ) (36) | G260fs | FS ins | ||
| TCGA-AP-A051 | Uterine (TCGA ) (36) | L169I | Missense | Low | |
| TCGA-AP-A0LM | Uterine (TCGA ) (36) | L368M | Missense | Medium | |
| TCGA-BS-A0UL | Uterine (TCGA ) (36) | R254S | Missense | Medium | |
| TCGA-BS-A0UF | Uterine (TCGA ) (36) | R381S | Missense | Medium | |
| TCGA-AX-A0J1 | Uterine (TCGA ) (36) | R408W | Missense | Low | |
| TCGA-N7-A4Y0 | Uterine CS (TCGA) | L204R | Missense | High | |
| HN_62671 | Head & neck (Broad) (39) | K142M | Missense | Medium | |
| HN_63080 | Head & neck (Broad) (39) | R175* | Nonsense | ||
| HN_62814 | Head & neck (Broad) (39) | V190M | Missense | High | |
| TCGA-CV-7178 | Head & neck (TCGA ) (in revision) | H147Q | Missense | Neutral | |
| TCGA-CN-4731 | Head & neck (TCGA ) (in revision) | R25* | Nonsense | ||
| TCGA-CQ-5325 | Head & neck (TCGA ) (in revision) | S351Y | Missense | High | |
| TCGA-CN-4730 | Head & neck (TCGA ) (in revision) | Y338fs | FS del | ||
| TCGA-D6-6516 | Head & neck (TCGA ) (in revision) | R264* | Nonsense | ||
| MEL-Ma-Mel-48 | Melanoma (Broad) (104) | S318L | Missense | Medium | |
| ME011 | Melanoma (Broad) (104) | T396I | Missense | Neutral | |
| TCGA-ER-A197 | Melanoma (TCGA provisional | K284E | Missense | Neutral | |
| TCGA-FW-A3R5 | Melanoma (TCGA provisional | L243F | Missense | Medium | |
| TCGA-FW-A3R5 | Melanoma (TCGA provisional | P217L | Missense | Medium | |
| TCGA-EE-A2MN | Melanoma (TCGA provisional | P252L | Missense | Medium | |
| TCGA-BR-4256 | Stomach (TCGA provisional) | F342L | Missense | Low | |
| TCGA-BR-4368 | Stomach (TCGA provisional) | M327T | Missense | Neutral | |
| TCGA-CG-5721 | Stomach (TCGA provisional) | T317M | Missense | Medium | |
| TCGA-BR-6452 | Stomach (TCGA provisional) | V337M | Missense | Low | |
| TCGA-AA-3854 | Colorectal (TCGA) (37) | A399V | Missense | Low | |
| TCGA-AG-A02N | Colorectal (TCGA) (37) | K125R | Missense | Low | |
| TCGA-AA-3972 | Colorectal (TCGA) (37) | R254C | Missense | High | |
| TCGA-AA-A01Z | Colorectal (TCGA) (37) | T339R | Missense | Neutral | |
| TCGA-AA-A00N | Colorectal (TCGA) (37) | E139K | Missense | Medium | |
| LUAD-74TBW | Lung adeno (Broad) (105) | E40V | Missense | Low | |
| LUAD-B00915 | Lung adeno (Broad) (105) | R160M | Missense | Medium | |
| TCGA-55-7576 | Lung adeno (TCGA) (in press) | H147Y | Missense | Neutral | |
| TCGA-05-4396 | Lung adeno (TCGA) (in press) | G62* | Nonsense | ||
| TCGA-05-4389 | Lung adeno (TCGA) (in press) | S250* | Nonsense | ||
| TCGA-60-2720 | Lung squ (TCGA) (106) | E387K | Missense | Neutral | |
| TCGA-66-2787 | Lung squ (TCGA) (106) | G137V | Missense | High | |
| BR-M-105 | Breast (Broad) (107) | G260fs | FS ins | ||
| TCGA-A2-A0CX | Breast (TCGA) (35) | H205Y | Missense | Medium | |
| TCGA-A8-A0A6 | Breast (TCGA) (35) | T228P | Missense | Medium | |
| ICGC_0037_TD | Pancreas (ICGC) (108) | V255I | Missense | Neutral | |
| TCGA-AK-3428 | Renal clear cell (TCGA) (109) | R309L | Missense | High | |
| TCGA-GV-A3QF | Bladder (TCGA) (110) | A161V | Missense | Low | |