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. Author manuscript; available in PMC: 2014 Sep 2.
Published in final edited form as: J Thorac Cardiovasc Surg. 2012 Sep 17;145(4):1077–1082.e4. doi: 10.1016/j.jtcvs.2012.07.059

Table 1. Transfusion requirements from day of last dose of study drug to CABG.

Variable <5 Days 6-7 Days >7 Days



Prasugrel (n = 88) Clopidogrel (n = 99) P value* Prasugrel (n = 34) Clopidogrel (n = 41) P value* Prasugrel (n = 50) Clopidogrel (n = 32) P value*
Intraoperative
 RBCs 0.62 ± 1.14 0.84 ± 1.14 .098 0.71 ± 1.69 0.59 ± 1.04 .945 0.34 ± 0.67 0.79 ± 1.91 .664
 Platelets 0.33 ± 1.20 0.22 ± 1.13 .300 0 ± 0 0.05 ± 0.32 .358 0.23 ± 1.46 0.29 ± 1.19 .669
 THCs 0.77 ± 2.24 0.47 ± 1.56 .267 0.09 ± 0.38 0.10 ± 0.45 .887 0.30 ± 1.49 0.74 ± 2.25 .485
 TDE 1.40 ± 2.64 1.30 ± 1.98 .511 0.80 ± 1.89 0.69 ± 1.08 .671 0.64 ± 1.65 1.53 ± 3.87 .974
Postoperative
 RBCs 2.02 ± 3.34 1.27 ± 1.77 .120 1.82 ± 2.44 0.92 ± 1.60 .154 1.06 ± 1.69 0.84 ± 1.24 .627
 Platelets 0.95 ± 2.84 0.25 ±1.14 .018 0.18 ± 0.53 0.08 ± 0.48 .127 0.15 ± 0.87 0.23 ± 1.09 .653
 THCs 2.31 ± 5.81 0.72 ± 2.09 .155 1.48 ± 3.13 0.64 ± 3.41 .006 0.75 ± 1.80 0.68 ± 1.83 .858
 TDE 4.34 ± 8.45 1.99 ± 3.28 .267 3.30 ± 5.14 1.56 ± 4.71 .107 1.81 ± 3.23 1.52 ± 2.71 .504
Total
 RBCs 2.64 ± 3.91 2.11 ± 2.24 .594 2.53 ± 2.96 1.51 ± 1.83 .297 1.40 ± 1.94 1.63 ± 2.69 .847
 Platelets 1.25 ± 3.25 0.47 ± 1.57 .039 0.18 ± 0.53 0.13 ± 0.57 .322 0.38 ± 1.67 0.52 ± 2.25 .793
 THCs 3.08 ± 6.56 1.18 ± 2.51 .194 1.58 ± 3.20 0.74 ± 3.42 .036 1.04 ± 2.52 1.42 ± 3.88 .888
 TDE 5.71 ± 9.45 3.29 ± 3.91 .556 4.11 ± 5.64 2.26 ± 4.73 .349 2.44 ± 3.80 3.05 ± 5.98 .548

Data presented as mean ± standard deviation. Number of subjects included those from last day of drug to surgery. RBCs, Red blood cells (packed RBCs, whole blood); TDE, total donor exposure (RBCs, platelets, cryoprecipitate, plasma); THCs, total hemostatic components (platelets, cryoprecipitate, plasma).

*

P < .05 (Kruskal-Wallis test).