Fig. 9.

Type I cell with demyelinated peripheral axon. A: Replacement of the myelinated peripheral axon and presomatic segment by a homogeneous fiber with nonmyelinated membrane of original Hodgkin-Huxley ion cannel densities causes slow spike propagation (comp. Fig. 7A). B: Transmembrane voltage of a central compartment; time axis zoomed to 1 ms. C: Transmembrane currents are essentially stronger in the unmyelinated fiber. D: Redrawn currents from Fig. 5B. The compartment length of a node-internode combination of (D) is represented by 5 compartments in (A–C). This factor 2.5 additionally reinforces the effect of current intensity already expressed by different scaling in (C) and (D).