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. Author manuscript; available in PMC: 2014 Sep 2.
Published in final edited form as: Vaccine. 2013 Jul 23;31(40):4330–4337. doi: 10.1016/j.vaccine.2013.07.020

Table 2. Mutagenesis to disrupt the antigenicity of epitope-M201.

Constructs Sequence IFAa Virus recovery
Wil d type 161AVKQGVVNLVKYAK174 +++ +++
Mut-1 .AAA.......... - -
Mut-2 ....AAA....... - -
Mut-3 .......AAA.... - -
Mut-4 ..........AAAA +++ NDb
Mut-5 ..AA.......... - -
Mut-6 .......A..A..A - -
a

IFA: indirect immunofluorescence assay with the MAb-201.

b

ND, not done.