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Plots of islets with various radii perfused with 3× PBS at 37, 22, and 8 °C. The solid line is model predictions under the same experimental conditions. The best fits for channel radius (corresponding to Ais) were 1.79, 2.08, 1.21 μm and correlation coefficients (R2) were 0.99, 0.99, 0.97, respectively.
