Table 5.
Scoring scheme 3 for colonic inflammation mediated by disturbed immune cell homeostasis
| Inflammatory cell infiltrate | Epithelial changes | Mucosal architecture | Score | |
|---|---|---|---|---|
|
| ||||
| Severity | Extent | |||
| Minimal | Mucosa | Minimal hyperplasia | 1 | |
| Mild | Mucosa, sometimes extending into submucosa | Mild hyperplasia, minimal goblet cell loss ± erosions | 2 | |
| Moderate | Mucosa and submucosa | Moderate hyperplasia ± few crypt abscesses, moderate goblet cell loss ± erosions | 3 | |
| Marked | Mucosa and submucosa | Marked hyperplasia ± several crypt abscesses and/or erosions | ± Irregular crypts or crypt loss ± ulcerations | 4 |
| Marked | Transmural | Marked hyperplasia ± multiple crypt abscesses | ± Irregular crypts or crypt loss ± ulcerations | 5 |