Table 2.
Correlation between Foxp3 Tregs and DCs density with clinicopathological parameters in NACT group
| Foxp3 Tregs (number of patients) | P value | r value | Dendritic cells (number of patients) | P value | r value | |||
|---|---|---|---|---|---|---|---|---|
|
|
|
|||||||
| Low | High | High | Low | |||||
| Lauren’s classification | ||||||||
| Intestinal | 7 | 8 | 0.347 | -0.128 | 4 | 11 | 0.035 | -0.282 |
| Diffuse | 25 | 16 | 24 | 17 | ||||
| Invasion depth | ||||||||
| T2 | 0 | 8 | 0.000 | -0.471 | 8 | 0 | 0.002 | 0.408 |
| T3/T4 | 32 | 16 | 20 | 28 | ||||
| TNM Stage | ||||||||
| I+II | 8 | 8 | 0.503 | -0.091 | 12 | 4 | 0.018 | 0.316 |
| III+IV | 24 | 16 | 16 | 24 | ||||
| Lymph node metastasis | ||||||||
| No | 15 | 12 | 0.821 | -0.031 | 20 | 7 | 0.000 | 0.465 |
| Yes | 17 | 12 | 8 | 21 | ||||
T2, tumor invades the muscularis propria or subserosa; T3, tumor invasion extends to or beyond the serosa; T4, tumor invades adjacent structures. P and r values obtained using Spearman rank correlation.