Table 2.

Clinico-pathological correlation of SEMA3A protein expression in gastric cancer tissues

Clinical parameters	Total	Sema3a expression			P-value
		Low (-~+)	Middle (++)	High (+++)
		(n = 70)	(n = 31)	(n = 27)
Gender					0.976
Male	88	48	21	19
Female	40	22	10	8
Age (years)					0.990
< 50	20	11	5	4
≥ 50	108	59	26	23
Tumor size (cm)					0.394
< 4	53	26	16	11
≥ 4	75	44	15	16
Location					0.924
Cardia	37	21	9	7
Body/Antrum	91	49	22	20
Growth pattern					0.403
Expanding type	65	33	19	13
Infiltration type	63	37	12	14
TNM stage					0.003*
Stage I/II	85	38	23	24
Stage III/IV	43	32	8	3
Differentiation					0.015*
Well/moderate	54	25	11	18
Poor	74	45	20	9
Depth of invasion					< 0.001*
T1/T2	80	32	23	25
T3/T4	48	38	8	2
H.pylori infection					0.142
Negative	46	23	9	14
Positive	82	47	22	13
Lymphnode metastasis					0.029*
Negative	61	29	13	19
Positive	67	41	18	8
Vascular invasion					0.001*
Negative	58	27	10	21
Positive	70	43	21	6
Distant metastasis					0.002*
M0	120	69	25	26
M1	8	1	6	1

^aStatistical analyses were performed by the Pearson χ ² test.

^* P-value < 0.05 was considered statistically significant.