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Immunohistochemical staining for prothymosin-α (PTMA) in normal and malignant colon tissue. A. Negative PTMA expression in normal colonic epithelium; B. Weak PTMA staining in a well-differentiated colorectal tumor; C. Diffuse, intense PTMA staining in a moderately to poorly differentiated colorectal tumor; D. Strong PTMA staining in a colon cancer lymph node metastasis sample. Original magnification ×200.
