Table 7.
Results of univariate and multivariate Cox’s models for overall survival of ovarian cancer patients
| Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|
|
|
|||||
| N | HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Age | |||||
| < 55 | 37 | 1.906 (0.949-3.828) | 0.070 | ||
| ≥ 55 | 28 | ||||
| Therapy | |||||
| Operation | 4 | 0.738 (0.176-3.090) | 0.677 | ||
| Operation+others | 61 | ||||
| Histological type | |||||
| Serous adenocarcinoma | 26 | 0.548 (0.274-1.099) | 0.090 | ||
| Non-Serous adenocarcinoma | 39 | ||||
| Stage | |||||
| I+II | 27 | 18.180 (4.315-76.591) | < 0.001 | 13.961 (3.220-60.528) | < 0.001 |
| III+IV | 38 | ||||
| Tumor differentiation | |||||
| Poorly | 54 | 0.371 (0.134-1.026) | 0.056 | 1.788 (0.791-4.041) | 0.163 |
| Otherwise* | 11 | ||||
| Lymph node metastasis | |||||
| Negative | 42 | 5.010 (2.421-10.370) | < 0.001 | 0.817 (0.267-2.494) | 0.722 |
| Positive | 23 | ||||
| Residual tumor | |||||
| Negative | 35 | 13.906 (5.241-36.900) | < 0.001 | ||
| Positive | 30 | ||||
| Caspase-3 | |||||
| Low | 47 | 4.538 (2.225-9.259) | 0.001 | 2.264 (1.100-4.661) | 0.026 |
| High | 18 | ||||
*
Otherwise means well-differentiated carcinoma and moderately-differentiated carcinoma.