. 2014 Jul 15;7(8):5057–5070.

Table 8.

Results of univariate and multivariate Cox’s models for overall survival of cervical cancer patients

		Univariate analysis		Multivariate analysis

	N	HR (95% CI)	P-value	HR (95% CI)	P-value
Age
< 55	88	0.869 (0.195-3.886)	0.855
≥ 55	16	0.869 (0.195-3.886)	0.855
Therapy
Operation	19	28.268 (0.098-8.183)	0.248
Operation+others	85	28.268 (0.098-8.183)	0.248
Stromal invasion
Negative	44	10.552 (1.380-80.693)	0.023	3.756 (0.416-33.934)	0.239
Positive	60	10.552 (1.380-80.693)	0.023	3.756 (0.416-33.934)	0.239
Vaginal wall extension
Negative	85	1.765 (0.553-5.631)	0.337	0.873 (0.243-3.142)	0.835
Positive	19	1.765 (0.553-5.631)	0.337	0.873 (0.243-3.142)	0.835
Parametrial extension
Negative	99	1.495 (0.195-11.439)	0.698
Positive	5	1.495 (0.195-11.439)	0.698
Intravascular space involvement
Absent	58	1.253 (0.439-3.573)	0.674
Present	46	1.253 (0.439-3.573)	0.674
Lymph node metastasis
Negative	76	7.363 (2.307-23.499)	0.001	5.134 (1.514-17.415)	0.009
Positive	28	7.363 (2.307-23.499)	0.001	5.134 (1.514-17.415)	0.009
Histological type
SCC	93	1.352 (0.302-6.040)	0.693
ADC+ASC	11	1.352 (0.302-6.040)	0.693
Stage
Early (in situ, I)	80	4.267 (1.337-13.619)	0.014	2.248 (0.621-8.137)	0.217
Advanced(II, III, IV)	24	4.267 (1.337-13.619)	0.014	2.248 (0.621-8.137)	0.217
Caspase-3
Low	93	7.478 (2.585-21.632)	<0.001	4.208 (1.373-12.894)	0.012
High	11	7.478 (2.585-21.632)	<0.001	4.208 (1.373-12.894)	0.012

Abbreviation: ADC+ASC: adenocarcinoma+adenosquamous carcinoma.