Table 2.
Logistic regression analysis on the association between the rs9548934 C>T polymorphism in hsa-miR-1 binding site in the 3’UTR of COG6 and risk of CAD
| Genotypes | Controlsa (n = 610) | CAD (n = 1013) | Adjusted ORb (95% CI) | ||
|---|---|---|---|---|---|
|
|
|
||||
| N | % | N | % | ||
| hsa-miR-1 binding site in COG6 rs9548934 C→T | |||||
| CC | 200 | 32.8 | 451 | 44.5 | 1.00 |
| CT | 286 | 46.9 | 391 | 38.6 | 0.66 (0.49-0.89) |
| TT | 124 | 20.3 | 171 | 16.9 | 0.98 (0.65-1.49) |
| CT/TT | 410 | 67.2 | 562 | 55.5 | 0.74 (0.56-0.97) |
| C allele | 43.8 | 36.2 | |||
a
The observed genotype frequency among the control subjects was in agreement with the Hardy-Weinberg equilibrium (x2 = 1.377, P = 0.240).
b
Adjusted for age, sex, BMI and smoking status.