Table 3.
Backward multi-variate analysis of SHH protein expression and other prognostic factors in 113 patients with GC
| Variables | Hazard ratio | 95% CI | P |
|---|---|---|---|
| Age (years) | |||
| < 60 | 1 | ||
| ≥ 60 | 2.643 | 1.477-4.302 | 0.007 |
| Pathologic staging | |||
| I-II | 1 | ||
| III-IV | 2.718 | 1.629-4.833 | 0.026 |
| Nodal status | |||
| N0 | 1 | ||
| N1-3 | 3.762 | 1.824-6.416 | 0.037 |
| Distant metastasis | |||
| Absent | 1 | ||
| Present | 2.106 | 1.718-5.429 | 0.008 |
| local recurrence | |||
| no | 1 | ||
| yes | 1.638 | 0.724-3.908 | < 0.001 |
| SHH overexpression | |||
| negative | 1 | ||
| positive | 1.187 | 0.614-4.736 | 0.041 |
CI: confidence interval; significance level: P < 0.05.