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. 2012 Mar 20;5(4):241–244.

Table 1.

Indications of amniocentesis and CVS


Indications Amniocentesis CVS
Number % Number %

High risk for major thalassemia 37 23.87 129 84.31
Advanced maternal age ≥35 30 19.35 3 1.96
Family history of Down syndrome 22 14.19
Family history of genetic disorder + high Risk in triple screening test 19 12.26 10 6.54
High risk in triple screening test 13 8.39
High risk for sickle cell 6 3.87 9 5.88
Previous births with fetal anomaly + high risk in first trimester screening test 6 3.87 1 0.65
Recurrent abortion history 5 3.23 1 0.65
High risk in triple test and advanced maternal age 4 2.58
High risk in first trimester screening test 2 1.29
Others 11 7.09