Figure 2.

Autophagosome density in mouse B cell subsets. Distribution of CytoID MFI in B cell subsets from bone marrow (BM) and spleens of 13-week-old NZB/W mice and age matched controls. Pre-B (CD19⁺IgM⁻IgD⁻), immature B (BM Imm, CD19⁺IgD⁻IgM⁺), mature B (BM Mat, CD19⁺IgD⁺IgM⁺), T1 (CD19⁺IgM⁺ IgD⁻CD23⁻CD21⁻), T2 (CD19⁺IgM⁺ IgD⁺CD23⁺CD21⁺), marginal zone (MZ, CD19⁺IgM⁺IgD⁻CD23⁻CD21^hi), follicular (FO, CD19⁺IgM⁻IgD⁺CD23^hiCD21⁺), and BM plasma cell (CD19^+/−CD138⁺) subsets are illustrated. n=5 mice per group. Box and whisker plots denote maximum and minimum, IQR, and median. *p<0.05; **p<0.01; ***p<0.001.