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. Author manuscript; available in PMC: 2014 Sep 2.
Published in final edited form as: Am J Ophthalmol. 2008 Nov 20;147(3):512–517.e2. doi: 10.1016/j.ajo.2008.09.004

TABLE 2.

Linkage Analysis Assuming Genetic Heterogeneity of the African-American and Whites Families

African Americans
Two-point Analysis
Multipoint Analysis
CHR. Mapa Marker MALOD α Marker Interval Map MALOD α
4 78.4 D4S2367 1.95 0.30 D4S2367-D4S3243 70.5 1.03 0.20
6 152.6 D6S2436 1.61 0.60 D6S2436-D6S1035 156.7 1.65 0.60
164.8 D6S1035 1.30 0.60 D6S1035-D6S1277 166.0 1.46 0.40
7 41.7 D7S1808 1.34 0.50 D7S1808-D7S817 46.0 1.87 0.60
50.3 D7S817 1.30 0.40 D7S817-D7S2846 54.0 1.15 0.50
Whites
Two-point Analysis
Multipoint Analysis
CHR. Map Marker MALOD α Marker Interval MAP MALOD α
6 137.7 D6S1009 2.87 0.90 D6S1040-D6S1009 130.2 2.19 1
12 36.1 D12S373 1.45 0.40 D12S373-D12S1042 42.3 2.42 1
48.7 D12S1042 1.29 0.90 D12S1042-GATA91H06 52.0 1.31 1
20 54.1 D20S478 2.46 1.00 D20S477-D20S478 48.7 2.14 0.7
62.3 D20S481 132 0.90 D20S478-D20S481 56.1 2.09 1
79.9 D20S480 1.50 0.60 D20S481-D20S480 69.1 1.76 0.6

CHR = ?; MALOD = maximum logarithm of the odds.

a

Map location in cM of the marker in two-point linkage or the position on the chromosome at which linkage is evaluated in multipoint linkage analysis.