Table 2. Overview of cis-encoded sRNAs from low-GC Gram-positive bacteria.
| Antisense RNA/Target-RNA | Length of sRNA (nt) | Species | Biological function | Mechanism | Specific characteristic |
|---|---|---|---|---|---|
| RatA/txpA | 222 | B. subtilis | antitoxin/toxin | RD | |
| SR4/bsrG | 180 | B. subtilis | antitoxin/toxin | RD + TI | bsrG temperature dependent |
| SR5/bsrE | 163b | B. subtilis | antitoxin/toxin | ? | |
| antibsrH/bsrHc | ≈202 | B. subtilis | antitoxin/toxinc | ? | |
| antiYonT/yonTc | ≈80 | B. subtilis | antitoxin/toxinc | ? | |
| ECF/yab | 750 | B. subtilis | autolysin | RD* | σX, σM |
| SprA1AS/SprA1 | 60 | S. aureus | antitoxin/toxin | RD | SprA1 is additionally a cytolisin and acts on human erythrocytes |
| RsaOX/sa0062* | 129 | S. aureus | transposase? | RD* | |
| RsaOW/is1181 | S. aureus | transposase? | ? | 8 RsaOW copies | |
| p3 RNA/glnA | 43 | C. acetobutylicum | N metabolism | ? | N-induced (p3) |
| Antisense/ubiG | 264/424/730/1000 | C. acetobutylicum | S metabolism | TINF | S-box riboswitch |
a Renamed (Jahn and Brantl, unpublished). bLength determined (Maiwald, Jahn, Brantl, unpublished). cNot yet demonstrated in Bacillus that indeed TA system. RD, RNA degradation; TI, translation inhibition; TINF, transcriptional interference; *, mechanism proposed but not experimentally substantiated; ?, no mechanism proposed.