Table 1.
Demographic and Clinical Data for Healthy Comparison Participants and Probands with Schizophrenia, Schizoaffective Disorder Depressed and Bipolar Types, and Psychotic Bipolar Disorder.
| Healthy comparisona (n=380) | Schizophreniab (n=297) | Schizoaffective Depressed Typec (n=61) | Schizoaffective Bipolar Typed (n=69) | Psychotic Bipolar Disordere (n=248) | Post Hoc† | |
|---|---|---|---|---|---|---|
| M (SD) | M (SD) | M (SD) | M (SD) | M (SD) | ||
| Age (years) | 37.71 (12.69) | 35.79 (12.72) | 38.38 (11.42) | 36.32 (12.12) | 36.22 (12.72) | - |
| Education (years) | 14.86 (2.56) | 12.75 (2.28) | 12.56 (2.05) | 13.19 (2.14) | 14.14 (2.40) | a, e>b, c, d |
| WRAT | 103.26 (13.94) | 94.19 (15.57) | 92.45 (15.49) | 98.65 (14.20) | 101.78 (14.06) | a, e> b, c; a>d; d>e |
| n (%) | n (%) | n (%) | n (%) | n (%) | ||
| Male | 178 (47) | 202 (68) | 30 (49) | 47 (38) | 91 (37) | b>a, c, d, e; a>e |
| Race | ||||||
| Caucasian | 233 (61) | 136 (46) | 31 (51) | 65 (52) | 186 (75) | e>a, b, c, d; a>b |
| African-American | 112 (30) | 138 (47) | 26 (43) | 52 (42) | 48 (19) | b, c, d>a>b |
| Other | 35 (9) | 23 (7) | 4 (6) | 7 (6) | 14 (6) | - |
| M (SD) | M (SD) | M (SD) | M (SD) | M (SD) | ||
| PANSS | ||||||
| Positive subscale | - | 16.80 (5.70) | 16.80 (5.39) | 18.63 (4.99) | 12.96 (4.65) | d>b, c>e |
| Negative subscale | - | 16.51 (5.83) | 16.39 (5.59) | 15.63 (4.87) | 11.90 (3.96) | b, c, d>e |
| YMRS | - | 5.52 (5.78) | 5.52 (6.03) | 8.43 (6.72) | 6.11 (6.99) | d>b, c, e |
| MADRS | - | 8.12 (7.96) | 15.07 (9.64) | 14.08 (10.35) | 10.16 (9.41) | c, d>b, e |
Abbreviations: WRAT, Wide Range Achievement Test-IV: Reading test; PANSS, Positive and Negative Syndrome Scale; YMRS, Young Mania Rating Scale; MADRS, Montgomery Asberg Depression Rating Scale
†
Post hoc tests were computed when the omnibus F test was significant at p<0.05.