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Deregulation of pro-apoptotic (A) and anti-apoptotic (B) Bcl2 family members in KrasG12D, p53thyr−/− primary tumors. qPCR was performed on RNA extracted from tumors with different prevailing histological components. C, Western blot analysis of the expression of selected pro- and anti-apoptotic proteins in the same tumors used for the RNA analysis above.
