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. 2014 Sep 3;34(36):11929–11947. doi: 10.1523/JNEUROSCI.1860-14.2014

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Copyright © 2014 the authors 0270-6474/14/3411929-19$15.00/0

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Figure 4. — Cell-specific markers and transcription factors. The top 40 genes and top 10 transcription factors ranked by fold enrichment of each cell type are listed. The most highly expressed genes are highlighted. Green, FPKM >150; blue, FPKM >50 for transcription factors. Fold enrichment of astrocytes, neurons, microglia, and endothelial cells are calculated as FPKM of one cell type divided by the average FPKM of all other cell types. Fold enrichment of OPC, NFO, and MO are calculated as FPKM of one cell type divided by the average FPKM of all non-oligodendrocyte-lineage cells, to highlight top genes specifically expressed by a particular maturation stage during oligodendrocyte development. Only highly expressed genes with FPKM >20 are included in the ranking to highlight genes that are most likely to have significant cell type-specific functions.