FIG. 4.

Cell viability (A), procollagen type I levels (B), and MMP-1 levels (C) in UVB-irradiated and CSE-treated cultured human dermal fibroblasts. Cells were irradiated with UVB (144 mJ/cm²) and then incubated in the absence or presence of CSE at concentrations ranging from 1 to 100 μg/mL for 72 h. Values are means±SD. # and * indicate significant differences (P<.05) between the UV (−) control and UV (+) control, respectively. ^#P<.05 and ^##P<.01 versus the normal control, **P<.01 versus UV-treated control.