FIG. 1.

Cytotoxicity of berberine and d-limonene, alone and in combination, on the growth of MGC803 cells. MGC803 cells were treated with berberine (C, D) and d-limonene (E, F), alone and in combination (G, H), at 1: 4, for 24 (C, E, G) and 48 h (D, F, H), with cisplatin (A for 24 h, B for 48 h) as a positive control. The viability of cells was qualified by MTT assay, reported as fraction affected (fraction of cells affected by treatment), and data represent the mean±SD from three replicate wells. P<.01, compared with the control group.