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Pairwise interactions between Chrs. 4 and 6 (a) and Chrs. 8 and 15 (b). Effect plots for the two interactions with the highest LOD scores. The x-axis designates the genotype at the first locus, while the black, light gray, and dark gray lines show the effect of B6, heterozygous, and MRL alleles, respectively, at the interacting loci (inset). Note that the B6/B6 genotype (black line) for both interactions is required to elicit an interaction with the second locus.
