Table 2.
Solute measurements
| Solute | Fiber Group (n=20) | Control Group (n=20) | P Value |
|---|---|---|---|
| Indoxyl sulfate | |||
| Free concentration (mg/dl) | |||
| Baseline | 0.36±0.23 | 0.28±0.16 | 0.20 |
| Week 6 | 0.25±0.17 | 0.28±0.15 | |
| Percent change | −29 (−56, −12) | 0 (−20, 34) | 0.02 |
| Percent free | |||
| Baseline | 10.1±4.9 | 8.6±2.9 | 0.23 |
| Week 6 | 8.4±3.5 | 9.0±3.2 | |
| Percent change | −12 (−22, 1) | −1 (−17, 44) | 0.15 |
| Total concentration (mg/dl) | |||
| Baseline | 3.5±0.9 | 3.2±1.2 | 0.43 |
| Week 6 | 2.9±1.4 | 3.1±1.2 | |
| Percent change | −17 (−44, 1) | −5 (−16, 14) | 0.04 |
| p-Cresol sulfate | |||
| Free concentration (mg/dl) | |||
| Baseline | 0.27±0.15 | 0.22±0.13 | 0.26 |
| Week 6 | 0.21±0.14 | 0.23±0.14 | |
| Percent change | −28 (−46, 5) | 4 (−28, 36) | 0.05 |
| Percent free | |||
| Baseline | 8.5±4.8 | 6.9±2.0 | 0.19 |
| Week 6 | 6.6±2.4 | 7.1±2.2 | |
| Percent change | −14 (−28, −1) | 0 (−10, 37) | 0.04 |
| Total concentration (mg/dl) | |||
| Baseline | 3.3±1.5 | 3.2±1.3 | 0.82 |
| Week 6 | 2.9±1.6 | 3.1±1.4 | |
| Percent change | −8 (−34, 7) | −1 (−21, 8) | 0.63 |
Data are presented as the mean±SD or median (25th percentile, 75th percentile). The significance of differences at baseline was assessed using the unpaired t test. The significance of the effect of fiber was assessed using analysis of covariance.