Table 3.
Parameter | Fiber Group (n=20) | Control Group (n=20) | P Value |
---|---|---|---|
Predialysis weight (kg) | |||
Baseline | 82±25 | 82±18 | >0.99 |
Week 6 | 83±25 | 82±19 | |
Percent change | 0 (1, 2) | 1 (−1, 2) | 0.76 |
Urea nitrogen (mg/dl) | |||
Baseline | 65±22 | 61±19 | 0.61 |
Week 6 | 56±14 | 60±19 | |
Percent change | −12 (−29, 11) | 2 (−16, 7) | 0.62 |
Albumin by bromocresol purple (g/dl) | |||
Baseline | 3.7±0.3 | 3.6±0.3 | 0.37 |
Week 6 | 3.5±0.3 | 3.5±0.4 | |
Percent change | −3 (−6, 0) | −2 (−4, 3) | 0.12 |
Albumin by nephelometry (g/dl) | |||
Baseline | 4.2±0.4 | 4.1±0.5 | 0.69 |
Week 6 | 4.1±0.4 | 4.0±0.4 | |
Percent change | −3 (−7, 2) | −4 (−7, 1) | 0.79 |
Prealbumin (mg/dl) | |||
Baseline | 29±9 | 28±8 | 0.72 |
Week 6 | 27±6 | 31±10 | |
Percent change | −9 (−17, 11) | 7 (−3, 18) | 0.03 |
CRP (mg/dl)a | |||
Baseline | 1.0±1.1 | 0.6±0.5 | 0.22 |
Week 6 | 1.1±1.6 | 0.8±1.1 | |
Percent change | 47 (−28, 75) | 0 (−13, 46) | 0.11 |
Phosphate (mg/dl) | |||
Baseline | 6.3±2.5 | 5.5±1.9 | 0.31 |
Week 6 | 6.3±1.8 | 5.6±2.2 | |
Percent change | 2 (−11, 17) | 10 (−15, 23) | 0.79 |
KDQOL-36 scoreb | |||
Baseline | 72±15 | 73±16 | 0.91 |
Week 6 | 73±12 | 75±16 | |
Percent change | 0 (−4, 7) | 3 (−4, 6) | 0.68 |
Data are presented as the mean±SD, n, or median (25th percentile, 75th percentile). The significance of differences at baseline was assessed using the unpaired t test. The significance of the effect of fiber was assessed using analysis of covariance. CRP, C-reactive protein; KDQOL-36, Kidney Disease Quality of Life Short Form 36.
Six CRP values were <0.1 mg/dl (the limit of quantitation), but no participant had a value <0.1 mg/dl at both baseline and week 6.
One patient in the fiber group and four patients in the control group did not complete the KDQOL-36 at the end of the study.