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. 2014 Aug 8;9(9):1577–1585. doi: 10.2215/CJN.12691213

Table 1.

Conventional indications for RRT

Indication Reported Any Time before RRT (134) First Indication
All (134) Classic-Urgent (90) Classic-Delayed (44)
Time from admission to indication (h) 0.5 [0.0–3.3] 0.4 [0.0–1.6] 1.8 [0.3–16.7]
Time from indication to RRT (h) 4.8 [1.9–17.7] 2.5 [0.9–4.9] 23.8 [17.7–43.2]
Hyperkalemia K≥6 mEq/L 41 (30.6) 25 (18.7) 20 (22.2) 5 (11.4)
Severe acidosis (pH≤7.15) 70 (52.2) 48 (35.8) 26 (28.9) 22 (50.0)
Plasma urea>36 mmol/La 26 (19.4)b 15 (11.2) 14 (15.6) 1 (2.3)
Oliguria or anuria (urine output<0.3 ml/kg per hour for ≥24 h or anuria for ≥12 h) 40 (29.9) 39 (29.1) 28 (31.1) 11 (25.0)
Fluid overload with pulmonary edemac 12 (9.0) 7 (5.2) 2 (2.2) 5 (11.4)

Data are expressed as number (percentage) or median [interquartile range].

a

Equals BUN of 100.8 mg/dl.

b

Thirteen of 26 (50.0%) patients also had at least one other conventional indication.

c

All components listed had to be met: fluid accumulation>10% of weight, respiratory Sequential Organ Failure Assessment score≥3, and oliguria (urine output criteria for AKI stage 2 or 3 present). Stage 2, urine output<0.5 ml/kg per hour for ≥12 hours; stage 3, urine output<0.3 ml/kg per hour for ≥24 hours or anuria for ≥12 hours.