Table 3.
Covariate | Univariate Odds Ratio (95% CI) | P Value | Multivariate Odds Ratio (95% CI) | P Value |
---|---|---|---|---|
All patients on RRTa | ||||
Age (5 yr) | 1.18 (1.07 to 1.30) | 0.001 | 1.20 (1.06 to 1.36) | 0.01 |
Number of preexisting chronic illnessesb | 1.03 (0.84 to 1.27) | 0.77 | 0.94 (0.72 to 1.23) | 0.66 |
Study site | — | 0.15 | — | 0.90 |
Source of admission | — | 0.18 | — | 0.54 |
SAPS II score without age points | 1.07 (1.05 to 1.09) | <0.001 | 1.06 (1.04 to 1.09) | <0.001 |
Mechanical ventilation (ICU stay) | 3.65 (1.82 to 7.32) | <0.001 | 2.93 (1.23 to 6.96) | 0.02 |
Vasoactive drugs (ICU stay) | 3.10 (1.29 to 7.41) | 0.01 | 1.30 (0.41 to 4.12) | 0.66 |
Severe sepsis until day 5 | 1.99 (1.18 to 3.37) | 0.01 | 1.16 (0.61 to 2.24) | 0.58 |
Time from ICU admission to RRT (h) | 1.00 (0.99 to 1.01) | 0.93 | 1.01 (0.98 to 1.02) | 0.17 |
CRRT as initial modality | 0.50 (0.26 to 0.95) | 0.04 | 0.97 (0.42 to 2.21) | 0.94 |
Classic RRT (versus pre-emptive RRT) | 2.25 (1.31 to 3.86) | 0.003 | 2.05 (1.03 to 4.09) | 0.04 |
Patients on classic RRTc | ||||
Age (5 yr) | 1.21 (1.03 to 1.41) | 0.02 | 1.32 (1.09 to 1.62) | 0.01 |
Study site | — | 0.61 | — | 0.75 |
SAPS II score without age points | 1.07 (1.04 to 1.10) | <0.001 | 1.08 (1.04 to 1.12) | <0.001 |
Mechanical ventilation (ICU stay) | 6.36 (2.79 to 14.49) | <0.001 | 4.14 (1.57 to 12.39) | 0.01 |
Vasoactive drugs (ICU stay) | 2.30 (0.87 to 6.08) | 0.09 | 0.42 (0.09 to 1.76) | 0.40 |
Severe sepsis until day 5 | 1.85 (0.93 to 3.68) | 0.08 | 1.19 (0.48 to 2.94) | 0.71 |
CRRT as initial modality | 0.47 (0.20 to 1.06) | 0.07 | 0.96 (0.31 to 3.04) | 0.95 |
Classic-delayed RRT (versus classic–urgent RRT) | 3.37 (1.57 to 7.22) | 0.002 | 3.85 (1.48 to 10.22) | 0.01 |
CRRT, continuous RRT; 95 % CI, 95% confidence interval.
Model included all 239 patients. Hosmer–Lemeshow test=9.82; P=0.28.
In total, 10 of 239 (4.2%) patients with missing data were assumed to have no comorbidities.
Model included all 134 patients. Hosmer–Lemeshow test=3.13; P=0.93.