Stereo views of CAR bound to CVB3. The virus in each panel is represented as a grayscale surface. Domains D1 and D2 of CAR are colored red, and the transmembrane and cytoplasmic regions are green. a, CVB3 complexed with the full length CAR. b, Same as (a) but with density outside a radius of 200 Å removed to show domains D1 and D2 of CAR only (green dots indicate where the transmembrane regions start). c, Same as (a) but with density removed outside a radius of 154 Å to show the binding site of D1 in the CVB3 canyon. The yellow triangle defines the icosahedral asymmetric unit. d, The complex of CVB3 with the CAR D1D2 fragment.