TABLE 2.

Plasma trans-3′-hydroxycotinine (3HC) and norcotinine (NCOT) levels in EA and AD rats following s.c. nicotine

Data are presented as mean (S.D.).

Time Point	Plasma 3HC Level		Plasma NCOT Level
	EA	AD	EA	AD
	ng/ml plasma
10 min	< LOQ	< LOQ	< LOQ	< LOQ
30 min	< LOQ	1.4 (3.7)	2.4 (0.8)	2.7 (3.8)
1 h	1.4 (0.8)	1.4 (0.1)	3.5 (1.3)	3.3 (0.3)
2 h	2.9 (1.6)	2.8 (0.9)	7.7 (3.1)	5.2 (1.8)
4 h	2.9 (1.2)	4.0 (1.9)	7.6 (2.6)	7.8 (3.1)
8 h	1.7 (0.4)	4.0 (0.5)	3.8 (0.7)	6.3 (1.0)