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Latency (seconds) to avoid electrical foot shock (A) and the number of escapes (B) exhibited by male Wistar rats during the CAR test (see text). Animals (n = 8/group) were pretreated p.o. with vehicle (Veh; 1% CMC), ADX88178 (1, 3, 10, 30 mg/kg), or olanzapine (OLZ; 3 mg/kg). Each point represents the observed mean. ***P < 0.001 compared with the Veh group.
