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. 2014 Jul-Aug;67(4):274–279.

Table 2.

Dexamethasone Concentration or Percentage of Initial Concentration Remaining (Mean ± Standard Deviation) in Oral Mix SF Suspension Vehicle over 91 Days of Storage in Glass and Plastic Bottles and Plastic Syringes (25 °C) and in Glass and Plastic Bottles (4°C)*

Study Day Glass Bottles Plastic Bottles Plastic Syringes



25°C 4°C 25°C 4°C 25°C
0 (initial measured concentration; mg/mL) 0.987±0.051 0.987±0.051 0.987±0.051 0.987±0.051 0.987±0.051
7 100.1%±2.3% 99.1%±1.9% 100.3%±3.1% 97.5%±3.6% 97.7%±3.8%
14 99.6%±2.2% 99.1%±1.9% 96.8%±2.3% 99.3%±2.0% 99.2%±4.3%
21 99.5%±2.2% 98.6%±3.3% 98.8%±1.9% 100.1%±1.2% 100.0%±1.0%
28 98.1%±2.1% 99.4%±0.9% 97.7%±2.0% 99.6%±1.7% 99.3%±1.3%
35 100.7%±2.0% 97.9%±4.4% 97.1%±1.1% 100.7%±3.8% 96.5%±2.7%
49 99.3%±3.0% 100.7%±3.6% 97.7%±2.4% 99.4%±2.6% 101.1%±0.7%
63 100.1%±3.3% 97.2%±0.9% 98.4%±2.0% 100.7%±2.5% 99.2%±2.3%
77 98.7%±2.6% 98.8%±0.7% 98.9%±2.1% 98.5%±0.9% 98.4%±1.1%
91 97.7%±2.0% 99.0%±3.0% 98.9%±3.4% 97.8%±1.2% 99.9%±1.0%
*

Measured concentration on day 0 is reported as mean ± standard deviation of 3 samples, analyzed in duplicate. Percent of initial measured concentration on all study days was calculated from the mean ± standard deviation of 3 samples, analyzed in duplicate.

Nominal initial concentration of all suspensions was 1.0 mg/mL.