Table 3.
Adverse events (AEs) occurring for ≥ 5% subjects in any treatment group, regardless of relation to study drug (all-subjects-treated group)
| |
Chinese |
Caucasian |
||
|---|---|---|---|---|
| Sugammadex (n = 120) | Neostigmine (n = 111) | Sugammadex (n = 29) | Neostigmine (n = 31) | |
| Subjects with any AE (n, %) |
84 (70) |
91 (82) |
20 (69) |
26 (84) |
| Abdominal pain |
1 (1) |
6 (5) |
1 (3) |
1 (3) |
| Upper abdominal pain |
6 (5) |
2 (2) |
– |
2 (6) |
| Nausea |
10 (8) |
13 (12) |
4 (14) |
7 (23) |
| Odynophagia |
6 (5) |
3 (3) |
– |
– |
| Vomiting |
11 (9) |
11 (10) |
– |
– |
| Fatigue |
– |
– |
2 (7) |
– |
| Pyrexia |
16 (13) |
16 (14) |
2 (7) |
1 (3) |
| Sensation of foreign body |
7 (6) |
4 (4) |
– |
– |
| Cardiac anesthetic complication |
1 (1) |
6 (5) |
– |
4 (13) |
| Incision site pain |
28 (23) |
26 (23) |
– |
– |
| Procedural hypotension |
– |
– |
– |
5 (16) |
| Procedural nausea |
4 (3) |
7 (6) |
– |
– |
| Procedural pain |
10 (8) |
10 (9) |
13 (45) |
12 (39) |
| Procedural vomiting |
4 (3) |
7 (6) |
– |
– |
| Wound complication |
3 (3) |
2 (2) |
3 (10) |
3 (10) |
| Dizziness |
11 (9) |
21 (19) |
2 (7) |
– |
| Headache |
5 (4) |
6 (5) |
1 (3) |
1 (3) |
| Insomnia |
2 (2) |
1 (1) |
2 (7) |
2 (6) |
| Vaginal hemorrhage |
5 (4) |
9 (8) |
– |
– |
| Increased upper airway secretion | 5 (4) | 10 (9) | – | – |