Change in depressive symptoms severity from baseline to month 16 follow-up in the CBT, TCC, and SS treatment groups. Total scores on the Inventory of Depressive Symptomatology-Clinician Rating Scale (IDS-C) range from 0 to 84, with higher scores indicating more severe depressive symptoms. Values are means; bars indicate standard error of measurement. Measurements were obtained at baseline and months 2 and 3 (mid-intervention), 4 (post-intervention), and 7 and 16 (follow-up). Shaded area indicates period of administration of intervention following baseline assessment. * Significant linear trend contrasts between CBT vs SS (t521.1 = 1.98.; P < 0.05). # Significant linear trend contrasts between CBT vs TCC (t523.0 = 1.98; P < 0.05). + Significant pairwise comparisons between TCC vs SS. Similar results were found when the sleep disturbance items of the IDS-C were removed. CBT, cognitive behavioral therapy; TCC, Tai Chi Chih; SS, sleep seminar.