Table 5.
Adipokines and oxidative stress markers in serum and plasma at baseline and after 12 weeks of intervention (Medians and 25th–75th percentiles)
High ALA-DAG (n 10) | High ALA-TAG (n 13) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Baseline | End of study | Baseline | End of study | ||||||||
Median | 25th–75th percentiles | Median | 25th–75th percentiles | P* | Median | 25th–75th percentiles | Median | 25th–75th percentiles | P† | P‡ | |
Adiponectin (ng/ml) | 2163 | 1689–3796 | 1982 | 1542–4046 | 0·6 | 2491 | 2253–3373 | 2530 | 2345–3069 | 0·8 | 1·0 |
Leptin (ng/ml) | 8·1 | 4·5–34·5 | 10·7 | 4·7–28·6 | 0·5 | 12·9 | 7·0–24·4 | 13·7 | 6·9–26·4 | 0·7 | 0·4 |
Resistin (ng/ml) | 10·6 | 9·3–13·6 | 10·5 | 9·5–13·7 | 1·0 | 10·7 | 7·7–12·5 | 11·6 | 8·1–12·5 | 0·5 | 0·7 |
Urine 8-iso-PGF2α (ng/g creatinine) | 161·1 | 118·7–243·4 | 178·3 | 134·6–272·5 | 0·7 | 244·3 | 157·1–306·0 | 255·8 | 162·9–352·2 | 0·5 | 0·7 |
α-Tocopherol:total lipids§ | 6·5 | 5·5–6·8 | 4·3 | 3·8–4·6 | 0·02 | 5·9 | 4·9–6·7 | 5·0 | 4·3–5·8 | 0·05 | 0·1 |
ALA, α-linolenic acid; DAG, diacylglycerol.
* Within the high-ALA-DAG group (prior to Bonferroni correction).
† Within the high-ALA-TAG group (prior to Bonferroni correction).
‡ Comparing change from baseline to the end of the study between the high-ALA-DAG and high-ALA-TAG groups (prior to Bonferroni correction).
§ The plasma concentration of α-tocopherol is normalised to the α-tocopherol to total lipid concentration (α-tocopherol/total cholesterol + TAG), expressed as the plasma α-tocopherol:plasma total lipid ratio.