Figure 1. Flowchart for CPAP and MAS data acquisition.

Patients were participants in a randomized crossover trial to compare health outcomes of one-month optimal treatment of CPAP and MAS. Patients underwent an acclimatization period to both MAS and CPAP (in a randomized order) before being randomized to one month of full treatment with either device. Therapeutic CPAP pressure was determined during the CPAP acclimatization period. Treatment efficacy was assessed by overnight polysomnography at the end of each treatment period. Patients underwent a 2-week washout period of no treatment before commencing one month of the alternate treatment. Arrows indicated the points at which data in this analysis was acquired.