Table 3.
Pathway analysis based on gene ontology in the Webgestalt pathway analysis tool with eighteen up-regulated genes with a fold-change >1·4 or down-regulated with a fold-change <0·7
| Pathway (total number of genes in pathway) | O | E | R | P | Adjusted P |
|---|---|---|---|---|---|
| Regulation of apoptosis (729) | 5 | 0·97 | 5·15 | 0·0021 | 0·044 |
| Includes Ptgs2 and Itga1 | |||||
| Regulation of angiogenesis (59) | 2 | 0·08 | 25·47 | 0·0027 | 0·044 |
| Includes Serpine1 | |||||
| Cell chemotaxis (47) | 2 | 0·06 | 31·97 | 0·0017 | 0·044 |
| Includes Itga1 | |||||
| Regulation of anatomical structure size (347) | 4 | 0·46 | 8·66 | 0·001 | 0·044 |
| Includes Ptgs2, Limk1 and Itga1 | |||||
| Developmental growth (173) | 3 | 0·23 | 13·03 | 0·0015 | 0·044 |
| Includes Ptgs2, Limk1 and Serpine2 | |||||
| Blood circulation (204) | 3 | 0·27 | 5·09 | 0·0023 | 0·044 |
| Includes Ptgs2 and Itga1 | |||||
| Oxidoreductase activity, acting on single donors with incorporation of molecular oxygen (38) | 2 | 0·04 | 47·65 | 0·0008 | 0·034 |
| Includes Ptgs2 |
O, Observed number of genes; E, expected number of genes; R, O:E ratio.