Mice were overiectomized (OVX) and after 3w, given either P4+E2 or vehicle for 3d; they were then injected with MHV68, and remained on either hormone treatments or vehicle for 7d (A). Seven days after infection, MHV68 was detected in the cervices of mice treated with hormones, but absent in vehicle treated controls (B). n=4, p< .05