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. Author manuscript; available in PMC: 2014 Sep 3.
Published in final edited form as: Mucosal Immunol. 2013 Feb 6;6(6):1081–1090. doi: 10.1038/mi.2013.2

Figure 1. Productive and nonproductive R5 HIV-1 infection of CTE established from seronegative women.

Figure 1

Donor-matched blocks of human cervical tissue were inoculated ex vivo with R5 HIV-1BaL in the presence or absence of 3TC (5 µM). A. Kinetics of p24Gag release in culture supernatants of productive and nonproductive CTE, respectively (means ± SEM of 8 productive and 14 nonproductive tissues; *p≤0.05, Student’s T test for 3TC-untreated vs. treated CTE). B. HIV-1gagDNA levels determined in productive and nonproductive CTE 12 days post-infection in the presence or absence of 3TC (means ± SEM of 8 productive and 14 nonproductive CTE; *p≤0.05, Student’s T test between productive and nonproductive CTE inoculated with HIV-1 in the absence of 3TC).