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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Exp Eye Res. 2013 Nov 4;118:30–35. doi: 10.1016/j.exer.2013.10.020

Fig. 2.

Fig. 2

QTL analysis. Genome-wide one-dimensional scan analysis of 63 F2 Mfrprd6 homozygous mice at SNP intervals of ~20 cM yielded a significant modifier locus on Chromosome 1 and suggestive loci on Chromosomes 6 and 11. Sex chromosomes were not included in the analysis as there was no indication of gender effects on the disease phenotype. Genome-wide significance thresholds are indicated at p = 0.63 (dotted-dashed line), 0.10 (dotted line), 0.05 (dashed line) and 0.01 (solid line). lod: log of the odds ratio.