Table 1. Characteristics of subjects included in the study and their mtDNA copy number.
| Variables | Controls (n=208) | Patients (n=119) | P value |
|---|---|---|---|
| Age, mean (SD) |
54.5 (14.4) |
26.4 (7.6) |
<0.0001 |
| Range, years |
19 – 96 |
12 – 50 |
|
| Male [No. (%)] |
138 (66) |
60 (52) |
- |
| Female [No. (%)] |
70 (34) |
55 (48) |
0.012 |
| Diabetes Mellitus [No. (%)] |
45 (22) |
22 (18.5) |
0.590 |
| Hypertension [No. (%)] |
27 (13) |
11 (9.2) |
0.402 |
| mtDNA content, copy number [Mean (SD)] |
1.04 (0.36) |
1.20 (0.45) |
0.0004 |
| mtDNA content, copy number [Median (Range)] | 1.02 (0.39 – 3.82) | 1.12 (0.61 – 3.82) | 0.0004 |