Table 1. DAVID analysis results for significantly up- or down- regulated proteins in pterygium tissues.
| Term | Count | % | P-Value | Benjamini |
|---|---|---|---|---|
| Upregulated proteins | ||||
| structural molecule activity |
32 |
21.9 |
7.60E-14 |
2.20E-11 |
| nucleotide binding |
32 |
21.9 |
3.10E-02 |
4.00E-01 |
| cytoskeletal protein binding |
17 |
11.6 |
3.90E-05 |
1.90E-03 |
| peptidase activity |
11 |
7.5 |
6.00E-02 |
5.30E-01 |
| guanyl ribonucleotide binding |
10 |
6.8 |
1.40E-02 |
2.40E-01 |
| structural constituent of eye lens |
6 |
4.1 |
5.00E-07 |
3.70E-05 |
| glycosaminoglycan binding |
6 |
4.1 |
1.30E-02 |
2.50E-01 |
| phosphotransferase activity |
3 |
2.1 |
4.20E-02 |
4.50E-01 |
| Downregulated proteins | ||||
| structural molecule activity |
12 |
17.4 |
1.60E-04 |
1.70E-02 |
| peptidase activity |
7 |
10.1 |
4.30E-02 |
4.70E-01 |
| identical protein binding |
7 |
10.1 |
7.90E-02 |
6.50E-01 |
| carbohydrate binding |
6 |
8.7 |
2.50E-02 |
3.70E-01 |
| protein binding, bridging |
5 |
7.2 |
9.80E-04 |
6.80E-02 |
| glycosaminoglycan binding |
5 |
7.2 |
4.20E-03 |
1.40E-01 |
| polysaccharide binding |
5 |
7.2 |
5.90E-03 |
1.70E-01 |
| oxidoreductase activity, acting on peroxide as acceptor |
3 |
4.3 |
9.80E-03 |
2.10E-01 |
| antioxidant activity |
3 |
4.3 |
2.00E-02 |
3.30E-01 |
| integrin binding |
3 |
4.3 |
3.10E-02 |
3.90E-01 |
| growth factor binding | 3 | 4.3 | 8.70E-02 | 6.60E-01 |
The Categories “GO-Molecular Function” were selected for testing. Term, specific terms within DAVID-categories; p value, p values for enrichment calculated by the EASE method used in DAVID; Benjamini, p values corrected for multiple testing by the Benjamini Hochberg method.