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. 2014 Mar 1;9(5):526–533. doi: 10.4103/1673-5374.130083

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Increased presence of Notch1 receptor and Hes1 in the temporal lobe of temporal lobe epilepsy (TLE) patients.

Immunohistochemistry for Notch1 receptor and Hes1 in the temporal neocortex of a patient without epilepsy (A1, B1) and a patient with intrac-table epilepsy (A2, B2). Notch1 receptor and Hes1 immunoreactive cells are indicated by arrows. Notch1 receptor- (A3) and Hes1 (B3)-immu-noreactivites cells in normal brain tissue and the brain of an intractable epilepsy patient. Values are presented as mean ± SD. Unpaired two-tailed Student's t-test was conducted to compare differences among the different groups. ^aP < 0.05, vs. control group.