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. 2014 Sep 3;9(9):e104525. doi: 10.1371/journal.pone.0104525

Table 3. Association risk SNPs in previous study and current study.

		European cohort⁷	British, Australia cohort⁸	Han Chinese cohort⁹	Current study
SNP	Minor allele	Allele frequency^a	Allele frequency^a	Allele frequency^a	Allele frequency^a	OR (95% CI)^b	P-value^b	HWE^c
rs3734523	A	0.09/0.12			0.02/0.04	0.58 (0.33–1.00)	0.052	0.265
rs4672495	G	0.36/0.32			0.17/0.19	0.89 (0.67–1.17)	0.400	0.632
rs10865331	A	0.43/0.36	0.45/0.37	0.54/0.48	0.53/0.47	1.65 (1.21–2.23)	0.001 ^**	0.817
rs11209032	G		0.36/0.33		0.49/0.49	1.04 (0.26–1.96)	0.794	0.073
rs27434	G	0.26/0.21		0.55/0.53	0.46/0.50	0.86 (0.94–1.96)	0.347	0.336
rs13210693	G			0.47/0.44	0.52/0.48	1.38 (1.96–2.06)	0.039	0.867

χ²-test was applied for testing genotype frequencies of SNPs in controls and patients with AS.

**Significant (p<0.0017) value is in bold.

^a

Allele frequency in case/control.

^b

The OR and P-value were showed for dominant model of SNPs.

^c

HWE were performed by chi-square.

^7,8,9

The reference numbers are as the same as that in the text.