Table 4. Difference in disease activity scores in the AS patients stratified by genotypes.
| SNP | Genotype | BASDAI | BASFI | BAS-G |
| rs3734523 | AA | 3.84 | 4.01 | 5.00 |
| AG | 3.61±2.48 | 1.35±2.23 | 3.79±3.07 | |
| GG | 4.32±2.19 | 2.03±2.16 | 4.41 ± 2.73 | |
| Unadjusted p value | 0.289 | 0.170 | 0.538 | |
| Adjusted p value | 0.361† | 0.194§ | 0.573† | |
| rs4672495 | GG | 3.99±2.63 | 0.79±0.82 | 4.13 ± 2.80 |
| GT | 4.22±2.31 | 2.06±2.25 | 4.31 ± 2.76 | |
| TT | 4.32±2.15 | 2.08±2.24 | 4.42 ± 2.76 | |
| Unadjusted p value | 0.847 | 0.210 | 0.862 | |
| Adjusted p value | 0.737† | 0.275§ | 0.888† | |
| rs10865331 | AA | 4.66±2.09 | 2.35±2.34 | 4.66 ± 2.73 |
| AG | 4.16±2.22 | 2.13±2.32 | 4.31 ± 2.75 | |
| GG | 4.22±2.25 | 1.47±1.69 | 4.22 ± 2.68 | |
| Unadjusted p value | 0.132 | 0.033* | 0.391 | |
| Adjusted p value | 0.104† | 0.133§ | 0.500† | |
| rs11209032 | AA | 4.61±2.10 | 2.11±2.36 | 4.56 ± 2.55 |
| AG | 4.09±2.10 | 1.97±2.12 | 4.32 ± 2.77 | |
| GG | 4.34±2.44 | 2.12±2.32 | 4.36 ± 2.90 | |
| Unadjusted p value | 0.096 | 0.941 | 0.604 | |
| Adjusted p value | 0.156† | 0.467§ | 0.737† | |
| rs27434 | GG | 4.56±2.12 | 2.05±2.08 | 4.53 ± 2.50 |
| AG | 4.17±2.28 | 2.03±2.14 | 4.50 ± 2.85 | |
| AA | 4.33±2.11 | 1.61±1.92 | 3.84 ± 2.60 | |
| Unadjusted p value | 0.593 | 0.364 | 0.083 | |
| Adjusted p value | 0.407† | 0.331§ | 0.125† | |
| rs13210693 | AA | 4.37±2.30 | 1.93±2.20 | 4.10 ± 2.79 |
| AG | 4.18±2.20 | 1.95±2.21 | 4.26 ± 2.66 | |
| GG | 4.60±2.07 | 2.28±2.09 | 4.83±2.75 | |
| Unadjusted p value | 0.203 | 0.209 | 0.127 | |
| Adjusted p value | 0.271† | 0.368§ | 0.100† | |
BAS, Bath Ankylosing Spondylitis; DAI, Disease Activity Index; FI, Function Index; G, Global. Data are presented as the mean ± standard deviation. The Kruskal-Wallis test is applied to exam the difference in disease activity scores in the AS patients stratified by genotypes.
†
Adjusted for the effects of age and gender.
§
Adjusted for the effects of age, gender, and disease duration. Significant (p<0.05) values are in bold.