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. 2014 Sep 3;9(9):e105903. doi: 10.1371/journal.pone.0105903

Table 2. Accuracy of plasma M30 and serum ALT, AST and GGT for prediction of NAFLD.

Cut-off, U/L or IU/L* Sensitivity, % Specificity, % PPV, % NPV, %
Plasma M30 162 95.7 45.0 89.0 69.2
263 74.2 95.0 98.6 44.2
278 67.7 100 100 40.0
Serum ALT 27 95.7 55.0 90.8 73.3
35 90.3 95.0 98.8 67.9
47 73.1 100 100 44.4
Serum AST 21 92.5 55.0 90.5 61.1
33 65.6 100 100 38.5
Serum GGT 32 90.3 50.0 89.4 52.6
46 78.5 80.0 94.8 44.4
55 62.4 95.0 98.3 35.2

ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma glutamyl transpeptidase; NAFLD, non-alcoholic fatty liver disease; PPV, positive predictive value; NPV, negative predictive value.

* Cut-off with high sensitivity, highest overall accuracy and high specificity were presented.

Cut-off for highest overall accuracy and high specificity were the same.