Table 3. Accuracy of plasma M30 and serum ALT, AST and GGT for prediction of NASH.

	Cut-off, U/L or IU/L*	Sensitivity, %	Specificity, %	PPV, %	NPV, %
Plasma M30	293	71.8	40.7	46.7	66.7
	432	56.4	63.0	52.4	66.7
	474	43.6	64.8	47.2	61.4
Serum ALT	53	79.5	40.7	49.2	73.3
	67	71.8	59.3	56.0	74.4
	100	41.0	79.6	59.3	65.2
Serum AST	30	84.6	40.7	50.8	78.6
	48	69.2	77.8	69.2	77.8
	65	43.6	90.7	77.3	69.0
Serum GGT	49	84.6	42.6	51.6	79.3
	84	64.1	70.4	61.0	73.1
	109	46.2	77.8	60.0	66.7

ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma glutamyl transpeptidase; NASH, non-alcoholic steatohepatitis; PPV, positive predictive value; NPV, negative predictive value.

* Cut-off with high sensitivity, highest overall accuracy and high specificity were presented.