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. 2014 Sep 3;9(9):e106101. doi: 10.1371/journal.pone.0106101

Table 5. Sensitive model parameters.

Physiological Parameters Partition Coefficients Chemical specific model parameters
Adult Humans QCC, QLC, QRC, BW,VPC, VFC, VLC, VRC, VSC Pfat, Prich, Pslow, Pliver Kmliverd, VmaxliverdC, KmetdC, GEdC, K3dC, K5dC, GElC, K3lC, K5lC
Children QCC, QLC, QRC,BW, VPC, VFC, VLC, VRC,VSC, Age Pfat, Prich, Pslow,Pliver, Pbrain Kmliverd, VmaxliverdC, KmetdC, GEdC, K3dC, K5dC, GElC,K3lC, K5lC, Kmliverl, VmaxliverlC
Adult Monkeys QCC, QLC, QRC, QFC, QSC, BW, VPC, VLC,VRC, VSC Pfat, Prich, Pslow,Pliver, Pbrain Kmliverd, VmaxliverdC, KmetdC, GEdC, K3dC, K5dC, GElC, K3lC, K5lC
Juvenile Monkeys QCC, QLC, QRC,QFC, QHC, QSC, BW, VPC,VFC, VLC, VRC, VSC Pfat, Prich, Pslow,Pliver, Pbrain Kmliverd, VmaxliverdC, KmetdC, GEdC, K3dC, GElC, K3lC, Kmliverl,VmaxliverlC, KmetlC

Parameters with absolute NSC values greater than 1 are highlighted in bold.